Table 4.
Five-Year Endothelial Cell Density (ECD) in Eyes with a Successful Transplant (N = 347)
| Donor Age | N | Baseline ECD* [Median (Interquartile Range)] (cells/mm2) | 5-Year ECD [Median (Interquartile Range)] (cells/mm2) | % Change from Baseline to 5 Years† [Median (Interquartile Range)] |
|---|---|---|---|---|
| Overall | 347 | 2698 (2481–2895) | 778 (574–1267) | −70% (−77% to −55%) |
| 66.0–<76.0 | 108 | 2585 (2445–2792) | 654 (538–986) | −75% (−79% to −62%) |
| 2.0–<66.0 | 239 | 2731 (2503–2924) | 824 (613–1342) | −69% (−77% to −51%) |
| 156.0–<66.0 | 109 | 2700 (2481–2904) | 748 (587–1127) | −70% (−78% to −56%) |
| 41.0–<56.0 | 82 | 2674 (2494–2850) | 787 (584–1416) | −71% (−77% to −46%) |
| 12.0–<41.0 | 48 | 2858 (2715–3090) | 1048 (793–1432) | −63% (−72% to −51%) |
Includes baseline ECD from eye bank for 118 eyes and from reading center for 229 eyes.
Endothelial cell density at 5 years minus ECD at baseline divided by ECD at baseline and multiplied by 100%. A negative number indicates loss of cells.