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. Author manuscript; available in PMC: 2011 Oct 27.
Published in final edited form as: Transplantation. 2010 Oct 27;90(8):836–842. doi: 10.1097/TP.0b013e3181f1db5d

Figure 5.

Figure 5

Correlation of percentages of beta cell apoptosis and in vivo functionality of transplanted human islets into streptozotocin-diabetic NODscid mice (n=59): Laser scanning cytometry data for beta-cell-specific apoptosis were plotted against blood glucose data of diabetic NODscid mice obtained 3-5 weeks post-transplantation and analyzed (A) by a two tailed t-test and (B) ROC curve analysis, giving a negative predictive value of 1.00 for 4.2% apoptotic beta cells and a positive predictive value of 0.85 for 2.4% apoptotic beta cells .