Table 1.
Basic characteristics of RAS patients and non-RAS patient controls
| Non-RAS patients (n=60) |
RAS patients (n=49) |
P-Value Non-RAS vs RAS |
|
|---|---|---|---|
| MBG (nM) | 0.20 ± 0.06 | 0.77 ± 0.06 | <0.01 |
| Demographic characteristics | |||
| Age (y) | 61.4 ± 1.5 | 70.5 ± 1.3 | <0.01 |
| Female, n (%) | 28 (46) | 30 (61) | 0.18 |
| Caucasian, n (%) | 52 (87) | 45 (92) | 0.54 |
| BMI | 31.1 ± 1.1 | 28.9 ± 0.8 | 0.10 |
| Systolic BP (mm Hg) | 131 ± 2 | 159 ± 5 | <0.01 |
| Diastolic BP (mm Hg) | 77 ± 1 | 76 ± 2 | 0.57 |
| Heart Rate (bpm) | 68 ± 1 | 67 ± 2 | 0.63 |
| Indications for treatment | |||
| Hypertension | 43 (72) | 48 (98) | <0.01 |
| Angina | 24 (40) | 23 (47) | 0.56 |
| Laboratory Values | |||
| Serum Creatinine (mg/dL) | 0.98 ± 0.03 | 1.11 ± 0.06 | 0.07 |
| MDRD GFR | 78.3 ± 4.4 | 64.7 ± 3.7 | 0.02 |
| Risk Factors, n (%) | |||
| CAD | 32 (53) | 34 (69) | 0.08 |
| Diabetes Mellitus (DM) | 15 (25) | 11 (22) | 0.82 |
| History of Smoking | 31 (52) | 34 (69) | 0.08 |
| Medications, n (%) | |||
| ACE inhibitors/ARB | 18 (31) | 23 (47) | 0.08 |
| Diuretics | 14 (24) | 23 (47) | 0.02 |
BMI, body mass index; BP, blood pressure; ACEi, angiotensin-converting enzyme inhibitors; ARB, angiotensin II receptor blockers, and CAD, coronary artery disease; RAS, renal artery stenosis. Values are mean ± SE or number and percentage of patients.