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To demonstrate that mAbA9 fulfils the criteria of a non-anaphylactogenic Ab, RBL cells were incubated with serum of Bet v1a-immunized mice and subsequently stimulated with Bet v1a, mAbA9, and two different anti-IgE Abs (EM95-3 and 84-1C). Values are means ± SD of three degranulation assays.
