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PGC-1α−/− significantly attenuated expressions of myocardial SOD2, Prx3, Prx5, Trx2, and TrxR2 Protein or mRNA. PGC-1α−/− significantly attenuates mRNA contents (C) and protein expressions of myocardial mitochondrial antioxidants SOD2, Prx3, Prx5, Trx2, and TrxR2 under control conditions or after TAC (A, B). Data are normalized to wild-type control mice. *p < 0.05 compared to the corresponding control; #p < 0.05 compared to wild type.
