Table III.
Incidence and severity of EAE in PPAR-α agonist-treated mice
Incidence | MCS Day 32a | Mean Severityb | |
---|---|---|---|
Gemfibrozil fed | 5/5 | 0.8 | 2.4 |
Fenofibrate fed | 6/7 | 0.9 | 2.0 |
EtOH fed | 4/4 | 2.0 | 2.8 |
DMSO fed | 6/6 | 2.5 | 3.5 |
Mean clinical disease score of individual animals in each treatment group at day 32 postimmunization (day 18 posttreatment).
Mean of the maximum clinical disease score of individual animals in each treatment group.