Table 1.

Local anesthetic activity of Spilanthes acmella Murr on intracutaneous wheal in guinea pigs

Group	Drug	No. of negative response	Mean % failure of response
A (Control)	0.9% saline	1.5 ± 0.76	4.16
B (Test)	10% SAM	25.33 ± 3.27*	70.36*
C (Test)	20% SAM	31.33 ± 1.08*	87.02*
D (Standard)	2% xylocaine	35.00 ± 0.51*	97.22*

^*P<0.001 when compared to control; n=6 in each group