FIG. 6.

Transduction of cells by the preformed targeted vector complexes. CD40⁺ Namalwa cells were infected with either Ad5.DR-HI40-Cd or Ad5.DR-LL-Cd at MOIs of 10 or 500 vp/cell, respectively. Each of the Cd-modified vectors was used either alone (−) or in association with the Fc-G28.5 ligand (+). Ad5.DR was used as an unmodified vector control. The infection was done with or without recombinant Ad fiber knob protein being added to the incubation mixture. The luciferase activity in the transduced cells is shown in relative light units. The standard deviations are represented by the error bars.