TABLE 2.

Effect of wild-type MVM on transduction of HT-1080 cells^a

Vector	Wild-type MVM	% of resistance in expt.						Avg % ± SDb
		G418			6TG
		1	2	3	1	2	3
None	−	0	0	0	0.0027	0.0015	<0.0008
None	+	0	0	0	0.0018	<0.0004	<0.007
Forward	−	6.0	3.6	NDc	0.013	0.012	ND
Forward	+	3.2	3.4	ND	0.012	0.013	ND
Reverse	−	4.8	2.7	1.7	0.0066	0.0035	0.0014	0.0034 ± 0.0023
Reverse	+	2.8	2.7	2.5	0.015	0.0092	0.0042	0.0095 ± 0.0054

^aIn three separate experiments, wild-type MVM (MOI, 2.5 RCV per cell) was added alone or in combination with the indicated MVM-HPe3TNA vector stock (MOI of 5 × 10⁵ genome-containing particles per cell). The percentage of G418- and 6TG-resistant cells was determined as described in Materials and Methods.

^bAverage values ± standard deviations (SD) are shown for the reverse vector.

^cND, not determined.