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. 2003 Dec;77(24):12941–12949. doi: 10.1128/JVI.77.24.12941-12949.2003

FIG. 3.

FIG. 3.

WNV burden in serum and the CNS in μMT mice after treatment with immune or nonimmune human gamma globulin. (A) Infectious virus levels in peripheral serum. μMT mice were treated immediately prior to infection with 10 mg of immune (lot G24191) or nonimmune (lot F43312) human gamma globulin. Serum was harvested at the indicated days, and virus levels were measured with a viral plaque assay in BHK21 cells. Data are shown as the average number of PFU per milliliter of serum and reflect at least three mice per time point. The dotted line represents the limit of sensitivity of the assay. (B) Infectious virus levels in the brain. Virus levels were determined in the brain after homogenization by plaque assay and normalized per gram of tissue. (C) Infectious virus levels in the spinal cord. Virus levels were determined from the spinal cord as described above.