TABLE 5.
Mortality of β2-m−/− mice due to WNV infection
| Dose (PFU/mouse) | Total no. of mice | No. of dead mice | Survival time (days) | Mortality (%) | MSTa (days) |
|---|---|---|---|---|---|
| 108 | 28 | 2 | 5 | 82 | 9.7 ± 2.9b |
| 2 | 6 | ||||
| 3 | 7 | ||||
| 3 | 8 | ||||
| 5 | 11 | ||||
| 3 | 12 | ||||
| 4 | 13 | ||||
| 1 | 14 | ||||
| 103 | 30 | 1 | 9 | 80 | 13.0 ± 2.0b |
| 2 | 10 | ||||
| 3 | 11 | ||||
| 5 | 12 | ||||
| 3 | 13 | ||||
| 2 | 14 | ||||
| 6 | 15 | ||||
| 2 | 16 |
Values represent MST ± standard deviation of mice which died up to 21 days after infection.
Statistically significant (P < 0.05) compared to B6 mice (see Materials and Methods for details).