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Thin-section TEM of RRV capsids. (A) Mixture of three morphologically distinct capsids prior to separation. A capsids (thick arrow) are empty icosahedral structures, B capsids (arrowhead) contain an inner ring-like structure likely composed of SCAF (see text), and C capsids (thin arrow) contain a dense core consistent with encapsidated viral DNA. Velocity sedimentation separated the mixed capsid population into distinct populations of A, B, and C capsids (B to D, respectively).
