TABLE 2.
Immunization and challenge schedulea
| Group | Macaque(s) | Immunization and schedule | Challenge |
|---|---|---|---|
| 1 | C623, C975, and C977 | rDIs (rDIsSIVGag), 106 PFU, i.v., wk 0 and 24 | SHIV-C2/1, 20-TCID50, i.v., wk 30 |
| 2 | C971, C973, and C978 | Control DIs (rDIsLacZ), 106 PFU, i.v., wk 0 and 24 | SHIV-C2/1, 20 TCID50, i.v., wk 30 |
| 3 | C699 and C972 | Naive, PBS, i.v., wk 0 and 24 | SHIV-C2/1, 20 TCID50, i.v., wk 30 |
Immunization and virus challenge were conducted simultaneously for all groups. The times of immunization and challenge were indicated as weeks after initial immunization. i.v., intravenous inoculation.