TABLE 5.

Effects of single doses of LNYS and DAMB on renal function parameters in plasma^a

Cohort and dosage (mg/kg)	Parameter level
	Creatinine (mg/dl)		BUN (mg/dl)		Potassium (mmol/liter)		Magnesium (mmol/liter)
	Baseline	24 h	Baseline	24 h	Baseline	24 h	Baseline	24 h
Controls	0.68 ± 0.02	0.68 ± 0.01	16 ± 0.66	15 ± 0.66	4.42 ± 0.10	4.45 ± 0.16	1.04 ± 0.05	0.98 ± 0.06
LNYS
2	0.66 ± 0.06	0.76 ± 0.06	15 ± 0.33	16 ± 0.57	4.27 ± 0.03	4.27 ± 0.12	0.95 ± 0.04	1.00 ± 0.01
4	0.70 ± 0.05	1.00 ± 0.15	19 ± 1.53	23 ± 1.20	4.30 ± 0.17	3.97 ± 0.20	0.92 ± 0.00	1.08 ± 0.08
6	0.66 ± 0.03	1.07 ± 0.08b	19 ± 0.33	23 ± 0.33b	4.50 ± 0.47	4.57 ± 0.37	0.93 ± 0.01	1.08 ± 0.04
DAMB, 1	0.60 ± 0.05	0.83 ± 0.06	18 ± 3.93	24 ± 2.73	4.27 ± 0.17	4.13 ± 0.23	0.92 ± 0.01	1.03 ± 0.02b

^aAll values represent the means ± SEM of results for three treated and six untreated animals each.

^bSignificantly different from results for controls at a P of <0.05 (t test).