TABLE 5.
Cohort and dosage (mg/kg) | Parameter level
|
|||||||
---|---|---|---|---|---|---|---|---|
Creatinine (mg/dl)
|
BUN (mg/dl)
|
Potassium (mmol/liter)
|
Magnesium (mmol/liter)
|
|||||
Baseline | 24 h | Baseline | 24 h | Baseline | 24 h | Baseline | 24 h | |
Controls | 0.68 ± 0.02 | 0.68 ± 0.01 | 16 ± 0.66 | 15 ± 0.66 | 4.42 ± 0.10 | 4.45 ± 0.16 | 1.04 ± 0.05 | 0.98 ± 0.06 |
LNYS | ||||||||
2 | 0.66 ± 0.06 | 0.76 ± 0.06 | 15 ± 0.33 | 16 ± 0.57 | 4.27 ± 0.03 | 4.27 ± 0.12 | 0.95 ± 0.04 | 1.00 ± 0.01 |
4 | 0.70 ± 0.05 | 1.00 ± 0.15 | 19 ± 1.53 | 23 ± 1.20 | 4.30 ± 0.17 | 3.97 ± 0.20 | 0.92 ± 0.00 | 1.08 ± 0.08 |
6 | 0.66 ± 0.03 | 1.07 ± 0.08b | 19 ± 0.33 | 23 ± 0.33b | 4.50 ± 0.47 | 4.57 ± 0.37 | 0.93 ± 0.01 | 1.08 ± 0.04 |
DAMB, 1 | 0.60 ± 0.05 | 0.83 ± 0.06 | 18 ± 3.93 | 24 ± 2.73 | 4.27 ± 0.17 | 4.13 ± 0.23 | 0.92 ± 0.01 | 1.03 ± 0.02b |
All values represent the means ± SEM of results for three treated and six untreated animals each.
Significantly different from results for controls at a P of <0.05 (t test).