TABLE 5.

Time-kill result

Drug and concn	No. of strains with indicated level of killinga at:
	3 h			6 h			12 h			24 h
	−1	−2	−3	−1	−2	−3	−1	−2	−3	−1	−2	−3
DK-507k
4 × MIC	12	11	6	12	12	8	12	12	11	12	12	12
2 × MIC	12	10	3	12	11	7	12	12	11	12	12	12
MIC	12	6	1	12	9	3	12	10	5	10	8	4
Sitafloxacin
4 × MIC	12	10	6	12	11	10	12	12	11	12	12	12
2 × MIC	12	10	3	12	10	8	12	12	11	12	12	12
MIC	10	5	0	12	9	1	12	9	7	9	7	5
Ciprofloxacin
4 × MIC	11	5	1	12	9	6	12	12	8	12	12	12
2 × MIC	10	5	1	12	7	5	12	12	8	12	12	11
MIC	8	4	1	11	4	0	12	10	4	6	5	4
Levofloxacin
4 × MIC	12	6	1	12	11	5	12	12	9	12	12	12
2 × MIC	12	5	1	12	10	4	12	12	9	12	12	12
MIC	7	3	0	11	5	2	12	8	5	8	6	5
Gatifloxacin
4 × MIC	12	8	3	12	11	6	12	12	9	12	12	12
2 × MIC	12	4	1	12	10	4	12	12	8	12	12	11
MIC	8	2	1	11	5	1	12	10	4	10	8	6
Moxifloxacin
4 × MIC	12	7	1	12	11	5	12	12	10	12	12	12
2 × MIC	11	5	1	12	11	4	12	12	9	12	12	11
MIC	10	1	0	10	5	1	11	8	5	9	8	7
Amoxicillin
4 × MIC	11	8	0	12	11	8	12	12	12	12	12	12
2 × MIC	10	8	0	12	11	7	12	12	11	12	12	12
MIC	8	5	0	11	9	4	11	11	8	10	8	7
Cefuroxime
4 × MIC	11	4	0	12	10	4	12	12	12	12	12	12
2 × MIC	10	4	0	12	9	4	12	12	12	12	12	12
MIC	10	2	0	12	8	4	12	11	7	9	7	6
Azithromycin
4 × MIC	7	2	0	11	7	4	12	11	8	12	12	12
2 × MIC	7	2	0	9	7	2	12	10	7	12	12	12
MIC	5	1	0	8	6	2	12	8	5	9	5	3
Clarithromycin
4 × MIC	8	3	0	11	7	3	12	11	7	12	12	12
2 × MIC	5	0	0	9	6	1	12	10	6	12	12	11
MIC	5	0	0	8	3	1	10	7	2	7	3	3

^a−1, 90% killing; −2, 99% killing; −3, 99.9% killing.