TABLE 2.
Fusr mutant | Competition index (SE) in mouse straina:
|
Fold improvement | |
---|---|---|---|
C57BL/6 | Cybb | ||
fusA1-7 | 5.1 × 10−1 (1.6 × 10−1) | 2.2 (5.0 × 10−1) | 4 |
fusA1-14 | 2.2 × 10−3 (4.4 × 10−3) | 9.2 × 10−2 (2.2 × 10−2) | 42 |
fusA1-15 | 1.2 × 10−3 (7.8 × 10−5) | 4.4 × 10−2 (1.5 × 10−2) | 37 |
fusA1 | <10−6 | 4.6 × 10−5 (2.4 × 10−5) | >46 |
Each result is expressed as a competition index, which is the ratio of mutant to wild type at the end of one growth cycle/the ratio of mutant to wild type at time zero. Each data point is the arithmetic mean of the bacterial ratios from the livers of six mice.