Figure 1.

Graphical representations of the key moieties that were appended to the water-soluble SWCNT-NH₂ by covalent-functionalization with radionuclides, DOTA, DFO, and antibodies (Note, not drawn to scale). A) Radioimmunotherapeutic drug Construct I (SWCNT-([²²⁵Ac]DOTA)(E4G10)). B) Radioimmunoimaging drug Construct II SWCNT-([⁸⁹Zr]DFO)(E4G10).

Abbreviations: SWCNT, single wall carbon nanotube; DOTA, 1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid; DFO, desferrioxamine B; ²²⁵Ac, actinium-225; ⁸⁹Zr, zirconium-89.