Figure 10.

A graphical illustration of the tumor vascular-targeting concept using the carbon nanotube constructs. The soluble, covalently functionalized, and radiolabeled constructs are delivered intravenously to the patient with tumor. The construct rapidly accesses the tumor vasculature and then can specifically bind to the monomeric VE-cad that is expressed in the neovasculature but cannot bind to resting vasculature with tight cell–cell contacts at the adherens junctions. (Note, Figures are not drawn to scale.)