TABLE 3.
Minimum inhibitory concentrations for in vitro transposition mutants
| Drug | MIC (μg/ml)
|
|||
|---|---|---|---|---|
| Clinical resistancea | S. typhimurium fosmid library | fSaltyGHK1 | fSaltyGHK2 | |
| Ciprofloxacin | 4 | 0.01563 | 0.03125 | 0.03125 |
| Levofloxacin | 8 | 0.03125 | 0.0625 | 0.0625 |
| Tetracycline | 16 | 2 | 8 | 8 |
| Doxycycline | 16 | 1 | 8 | 8 |
| Ampicillin | 32 | 4 | 16 | 16 |
| Ceftazidime | 32 | 0.125 | 0.5 | 0.5 |
| Cefotaxime | 64 | 0.125 | 1 | 1 |
| Cefuroxime | 32 | 16 | 64 | 64 |
| Cefoxitin | 32 | 16 | 128 | 128 |
| Cefepime | 32 | 0.125 | 1 | 1 |
a
Clinical resistance as defined by the NCCLS (13). MICs greater than the clinical resistance level are indicated in boldface.