Table 5.
Adverse events by patient following treatment with electronic brachytherapy alone or in combination with external beam radiation therapy as recorded at follow-up visits
| Patient number | AEs for patients treated with EBT and EBRT | Days post EBT (n) | CTC Gradea |
|---|---|---|---|
| 1-1 | Diarrhea | 5 | 1 |
| 1–2 | Diarrhea | 10 | 1 |
| 2-1 | Diarrhea, fatigue | 43 | 1, 2 |
| 3-1 | Erythema at introitus | 14 | 1 |
| 3-2 | Diarrhea | 36 | 1 |
| 4-1 | Dysuria, abdominal discomfort | 2 | 1 |
| Hemorrhoid, abdominal discomfort | 99 | 2, 1 | |
| 4-2 | Dysuria related to external beam therapy | 14 | 2 |
| Fungal skin rash related to external beam therapy | 14 | 2 | |
| Burning/flushing sensation at tumor site related to external beam | 13 | 2 | |
| Diarrhea related to external beam therapy | 13, 111 | 1, 2 | |
| 4-3 | Dysuria | 13 | 2 |
| Diverticulosis, hepatomegaly related to EBT | 111 | 1, 1 | |
| Renal stone (small right) | 111 | NA | |
| Dysuria (end micturition) | 38, 79 | NA | |
| Bladder spasms, occasional | 38, 79 | NA | |
| 4-4 | Chronic moist desquamation of vaginal mucosa | 79 | 3 |
| Vaginal discomfort/irritation | 38, 128 | NA | |
| Serosanguinous discharge with use of dilator (occasional) | 128 | NA | |
| 4–5 | Urgency (occasional) | 85 | NA |
| AEs for patients treated with EBT only | |||
| 5-1 | Blood-tinged mucous stool | 119 | NA |
| Superficial rectal ulcer with bleeding | 210, 266, 328 | 2 | |
| 6-1 | Anal discomfort, discomfort with intercourse | 125 | NA |
| 7-1 | Vaginal mucositis | 115 | 1 |
Note:
a
The AE Common Terminology Criteria (CTC) grade is shown if provided in the patient record.
Abbreviations: AE, adverse event; EBT, electronic brachytherapy; EBRT, external beam radiation therapy; NA, not available.