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Effect of Added NBu4OAc, NBu4PF6, and H2O on Reductive Elimination from 6
| Entry | Additive | Yield 7 | Yield 8a | Yield 8b |
|---|---|---|---|---|
| 1 | None | 54% | <2% | <2% |
| 2 | 0.2 equiv NBu4OAc | 26% | <2% | <2% |
| 3 | 1 equiv NBu4OAc | 2% | 16% | 16% |
| 4 | 1 equiv NBu4PF6 | 56% | <2% | <2% |
| 5 | 1 equiv H2O | 50% | <2% | <2% |
| 6 | 10 equiv H2O | 50% | <2% | <2% |
Conditions: Complex 6 (1 equiv) and the appropriate additive in DCE (0.26 mL) for 12 h at 60 °C. Yields were determined by 19F and 1H NMR spectroscopy and represent an average of at least two independent runs.
