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. Author manuscript; available in PMC: 2010 Oct 22.
Published in final edited form as: Anticancer Agents Med Chem. 2008 May;8(4):358–367. doi: 10.2174/187152008784220311

Figure 5.

Figure 5

Outline of the basic steps in the nonhomologous end-joining pathway for DNA double-strand break repair. PNK is required to process the strand break termini. In this pathway it interacts directly with phosphorylated XRCC4.