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. Author manuscript; available in PMC: 2010 Oct 22.
Published in final edited form as: Anticancer Agents Med Chem. 2008 May;8(4):358–367. doi: 10.2174/187152008784220311

Figure 7.

Figure 7

Mechanism of 5’ DNA phosphorylation catalyzed by the PNK kinase domain. The role of the catalytic Asp 396 (Asp 397 in human PNK) is highlighted.