TABLE 1.
Responses to selective adenosine receptor agonists
Populations of wild-type sperm were bathed (2–5 min) in HS medium alone or with the indicated additions. Shown are mean beat frequencies (n = 20–97 cells in 2–5 independent experiments).
| Treatment | Beat frequency | n |
|---|---|---|
| Hz | ||
| None | 3.45 ± 0.19a | 97 |
| DMSO (1%) | 3.27 ± 0.17a | 59 |
| Adenosine analog | ||
| Cl-dAdo (25 μm) | 6.32 ± 0.51d | 71 |
| A1R agonist | ||
| CCPA (100 μm) | 3.65 ± 0.18a | 62 |
| A2R agonist | ||
| CGS21680 (40 μm) | 2.50 ± 0.14b | 20 |
| A3R agonist | ||
| IB-MECA (100 μm) | 5.06 ± 0.37c | 53 |
| Cl-IB-MECA (30 μm) | 5.87 ± 0.53c,d | 42 |
a These groups did not differ (p > 0.05).
b–d These groups differed from a and from one another (p < 0.05).