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Comparison of the interaction modes of CART1, NCoR1, and NCoR2. The interactions were monitored by yeast two-hybrid assays using Gal4 AD-CART1 (clone H2), -NCoR1 (clone A2), or -NCoR2 (clone B2) and LexA DBD-RARα mutants (A) or LexA DBD-TRβ mutants (B). The range of amino acids in each mutant is indicated. Functional domains of RARα and TRβ were designated as A–F (or E for TR). Numbers represent the relative percent of wild-type β-galactosidase activity.
