Table 2. Summary of FePt Nanoparticles Cytotoxicity Studies Reported in the Literature^a.

			cytotoxicity
material	Fe precursorb	coating	cells	[NPs] (μg/mL)	[Fe] (μg/mL)	tinc (h)	cell damage (%)	ref
FePt-CoS2	Fe(CO)5	CoS2 shell	HeLa	1.5	∼0.007	24	50	(39)
FePt-Cys	Fe(CO)5	cysteine	HeLa	5	∼0.7	24	∼10	(39)
				15.5	∼2.5	24	50
FePt-Fe2O3	Fe(CO)5	Fe2O3 shell, l-DOPA coating	HeLa	∼8.3	∼0.045c	24	50	(37)
					∼3.8d
FePt-Fe3O4	Fe(CO)5	Fe3O4 shell	HeLa	40	e	24	∼10	(37)
				10	e	72	∼10
				20	e	72	∼30
FePt-COOH	Fe(CO)5	bilayer of phospholipid (DSPE-PEG(2000) carboxylic acid lipid) and oleic acid/oleylamine	HeLa	∼10.7	1.72	24	∼40	(52)
			A431	∼10.7	1.72	24	∼40
			SK-BR3	∼10.7	1.72	24	∼20
			HEK-293	∼10.7	1.72	24	∼30
			A2780	∼7.8	1.25	24	50
FePt-SiO2-A	Na2Fe(CO)4	SiO2 shell	A375M, MCF7, U2OS	200	∼2	168	0	f
FePt-A	Na2Fe(CO)4	cysteamine	A375M, MCF7, U2OS	30	∼5.3	168	0	f
				60	∼10.5	72	∼10

^aListed are NPs’ structure, precursors, and coating; “cells” stands for the cell line; [NPs] is the nanoparticle concentration; t_inc is the incubation time; cell damage is that after incubation.

^bPt precursor always Pt(acac)₂.

^cFe contribution from Fe₂O₃ shell not included.

^dFe contribution from Fe₂O₃ shell included.

^e[Fe] cannot be calculated.

^fData presented in this work.