Table 5.
Comparison of laboratory values in patients with acute cellular rejection before and 180 days after conversion to FK506
| Pre-FK506a (mean [range]) | Values at 180 daysa (mean [range]) | |
|---|---|---|
| CsA (days) | 219 (12–1401) | — |
| FK506 (days) | 343 (266–547) | — |
| TB (mg/dl) | 8.3 (0.6–30.3) | 0.5b (0.1–1.2) |
| AST (IU/L) | 96 (24–210) | 65c (21–141) |
| ALT (IU/L) | 219 (34–1229) | 82c (13–152) |
| ALP (IU/L) | 215 (56–429) | 164c (74–448) |
| gGTP (IU/L) | 284 (71–750) | 123c (22–440) |
| BUN (mg/dl) | 38 (5–101) | 36c (14–84) |
| CR (mg/dl) | 2.0 (0.1–5.0) | 1.9c (0.4–3.5) |
a
Patient with functioning grafts as of 9/01/90 (n=14).
b
P<0.05 (paired t test) compared with pre-FK506 values.
c
P>0.05 (paired t test) compared with pre-FK506 values.