Table 7.
Comparison of laboratory values in patients with an entry diagnosis of chronic rejection/CPH, and low-grade CAH beforehand and at 180 days following FK506 conversion
| Pre-FK506a values (mean [range]) | Values at 180 daysa (mean [range]) | |
|---|---|---|
| CsA (days) | 731 (170–1555) | — |
| FK506 (days) | 299 (264–344) | — |
| TB (mg/dl) | 1.1 (0.3–2.1) | 0.6b (0.1–1.3) |
| AST (IU/L) | 173 (21–411) | 85b (23–210) |
| ALT (IU/L) | 291 (45–805) | 110b (22–256) |
| ALP (IU/L) | 142 (81–308) | 154c (105–293) |
| gGTP (IU/L) | 413 (68–1540) | 309c (18–907) |
| BUN (mg/dl) | 26 (11–55) | 32c (12–92) |
| CR (mg/dl) | 1.6 (0.9–2.8) | 2.1b (1.0–4.4) |
a
In patients with functioning grafts as of 9/01/90 (n=16).
b
P<0.05 (paired t test) compared with pre-FK506 values.
c
P>0.05 (paired t test) compared with pre-FK506 values.