TABLE 1.
Subject | Day post-transplant | Time of study | Dose (mg) | Cmin (ng/ml) | CyA clearance |
|
---|---|---|---|---|---|---|
(ml/min) | (ml/min/kg) | |||||
1 | 21 | 2 p.m.–10 p.m. | 140 | 519 | 385 | 5.13 |
18 | 10 p.m.–6 a.m. | 140 | 301 | 536 | 7.14 | |
2 | 3 | 10 a.m.–6 p.m. | 150 | 391 | 337 | 4.32 |
3 | 8 p.m.–4 a.m. | 150 | 328 | 479 | 6.20 | |
5 | 9 a.m.–5 p.m. | 150 | 453 | 369 | 4.82 |
CyA, cyclosporine.