Table 3. Effect of Ets-1 over-expression in oxidative stress.
Pathway | Gene | GenBank ID | Gene name | Fold change |
Antioxidant defense | Glutathione peroxidase 1 | NM_000581.2 | GPX1 | +1.98 *** |
Glutathione peroxidase 2 | NM_005333 | GPX2 | +8.81 *** | |
Glutathione peroxidase 3 | NM_002084 | GPX3 | +4.19 *** | |
Peroxiredoxin 5 | NM_012094 | PRDX5 | +1.54 *** | |
ROS metabolism | Arachidonate 12-lipoxygenase | NM_000697 | ALOX12 | −1.81 ** |
GTF2I repeat domain containing 2 | NM_173537 | GTF2IRD2 | +1.92 *** | |
GTF2I repeat domain containing 2B | NM_001003795 | GTF2IRD2B | +2.19 *** | |
Neutrophil cytosolic factor 2 | NM_000433 | NCF2 | −2.24 *** | |
Superoxide dismutase 2 (mitochondrial) | NM_001024465 | SOD2 | −1.49 *** | |
ATX1 antioxidant protein 1 | NM_004045 | ATOX1 | +1.53 *** | |
Prion protein | NM_000311 | PRNP | −1.60 *** | |
Scavenger receptor class A, member 3 | NM_016240 | SCARA3 | +1.48 ** | |
Selenoprotein P, plasma, 1 | NM_005410 | SEPP1 | −2.04 *** | |
Aldehyde oxidase 1 | NM_001159 | AOX1 | +2.81 *** | |
BCL2/adenovirus E1B interacting protein 3 | NM_004052 | BNIP3 | +3.15 *** |
p≤0.05 = *, p≤0.01 = **, p≤0.001 = ***.