Table 4. Effect of Ets-1 over-expression on the ETC.
Component | Gene | GenBank ID | Gene name | Fold change |
Complex I | NADH dehydrogenase (ubiquinone) 1 α subcomplex 1 | NM_004541 | NDUFA1 | −1.60 *** |
NADH dehydrogenase (ubiquinone) 1 α subcomplex 9 | NM_005002 | NDUFA9 | −1.59 *** | |
NADH dehydrogenase (ubiquinone) 1, α/β subcomplex 1 | NM_005003 | NDUFAB1 | −2.23 *** | |
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 5 | NM_002492 | NDUFB5 | −1.50 *** | |
NADH dehydrogenase (ubiquinone) 1 β subcomplex 11 | NR_024234 | NDUFB11 | −1.48 *** | |
NADH dehydrogenase (ubiquinone) 1 α subcomplex assembly factor 1 | NM_016013 | NDUFAF1 | −1.71 *** | |
NADH dehydrogenase (ubiquinone) Fe-S protein 4 | NM_002495 | NDUFS4 | −1.58 *** | |
Complex III | Cytochrome c-1 | NM_001916 | CYC1 | −1.46 *** |
Ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1 | NM_006003 | UQCRFS1 | −1.50 *** | |
Ubiquinol-cytochrome c reductase, complex III subunit VII | NM_014402 | UQCRQ | −1.50 *** | |
Complex IV | Cytochrome c oxidase subunit 7b | NM_001866 | COX7B | −2.08 *** |
ATP Synthases | ATP synthase, H+ transporting, mitochondrial F1 complex, α subunit 1, cardiac muscle | NM_001001937 | ATP5A1 | −1.53 *** |
ATPase, H+ transporting, lysosomal accessory protein 2 | NM_005765 | ATP6AP2 | −1.50 *** | |
Electron transport associated factors | Cytochrome c, somatic | NM_018947 | CYCS | −1.51 *** |
Holocytochrome c synthase (cytochrome c heme-lyase) | NM_005333 | HCCS | −1.76 *** |
p≤0.05 = *, p≤0.01 = **, p≤0.001 = ***.