Table 2.
Common drugs used in recent clinical studies for platinum-resistant ovarian cancer.
| Number (%) | Subjects | RR (%) | |
|---|---|---|---|
| Clinical trials (n=40) | |||
| Gemcitabine | 10 (25%) | 430 | 22.3 |
| Pegylated liposomal doxorubicin | 8 (20%) | 339 | 22.4 |
| Topotecan | 4 (10%) | 96 | 19.9 |
| Cisplatin | 3 (7.5%) | 114 | 21.9 |
| Docetaxel | 3 (7.5%) | 61 | 19.7 |
| Non-trial studies (n=20) | |||
| Gemcitabine | 6 (30%) | 141 | 22.7 |
| Paclitaxel | 4 (20%) | 89 | 39.3 |
| Topotecan | 3 (15%) | 113 | 17.8 |
| Carboplatin | 3 (15%) | 62 | 27.4 |
| Pegylated liposomal doxorubicin | 2 (10%) | 53 | 28.3 |
| Bevacizumab | 2 (10%) | 32 | 37.5 |
Analysis of 60 clinical studies published between January 2005 and March 2010.
Abbreviations: Number, number of clinical studies; Subjects, sum of enrolled patients in clinical studies; and RR, average response rate in any regimens using the listed agent.