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. Author manuscript; available in PMC: 2011 Nov 1.
Published in final edited form as: Expert Opin Investig Drugs. 2010 Sep 6;19(11):1339–1354. doi: 10.1517/13543784.2010.515585

Table 2.

Common drugs used in recent clinical studies for platinum-resistant ovarian cancer.

Number (%) Subjects RR (%)
Clinical trials (n=40)
Gemcitabine 10 (25%) 430 22.3
Pegylated liposomal doxorubicin 8 (20%) 339 22.4
Topotecan 4 (10%) 96 19.9
Cisplatin 3 (7.5%) 114 21.9
Docetaxel 3 (7.5%) 61 19.7
Non-trial studies (n=20)
Gemcitabine 6 (30%) 141 22.7
Paclitaxel 4 (20%) 89 39.3
Topotecan 3 (15%) 113 17.8
Carboplatin 3 (15%) 62 27.4
Pegylated liposomal doxorubicin 2 (10%) 53 28.3
Bevacizumab 2 (10%) 32 37.5

Analysis of 60 clinical studies published between January 2005 and March 2010.

Abbreviations: Number, number of clinical studies; Subjects, sum of enrolled patients in clinical studies; and RR, average response rate in any regimens using the listed agent.