Fig. 2.

Time–course of serum immunoglobulin (Ig)A endomysium antibodies (EMA) and nuclear fluorescence reactivity (NFR) antibodies. The timing of serum IgA EMA and NFR antibody appearance/disappearance are plotted in the graph. The small boxes refer to the time–course of serum antibodies, from their appearance to disappearance (mean values). The great boxes refer to standard deviations of serum antibody disappearance times. At baseline, EMA are detectable in coeliac disease (CD) patients' sera and disappear after 76 ± 34 days from starting the gluten-free diet (GFD). At the latter time-point, serum NFR antibodies become observable and disappear in the following 75 ± 41 days, for a total of 151 ± 37 days from starting the GFD.