Table 2.
Association of Gene Expression Signatures and Clinical Variables with Clinical Outcome in Multivariate Analysis
| A: Late recurrence | ||||
|---|---|---|---|---|
| Variable | Hazard | 95% CI | p-value | |
| ratio | low | high | ||
| Late recurrence signature | 2.94 | 1.39 | 6.20 | 0.005 |
| B: Survival | ||||
|---|---|---|---|---|
| Variable | Hazard | 95% CI | p-value | |
| ratio | low | high | ||
| Survival signature | 2.08 | 1.03 | 4.18 | 0.04 |
| AFP > 100 ng/mL | 2.29 | 1.14 | 4.61 | 0.02 |
| Vascular invasion | 2.01 | 1.01 | 3.99 | 0.05 |
| C: Survival (longer follow-up patients, n=168) | ||||
|---|---|---|---|---|
| Variable | Hazard | 95% CI | p-value | |
| ratio | low | high | ||
| Survival signature | 2.56 | 1.22 | 5.38 | 0.01 |
| AFP > 100 ng/mL | 2.01 | 0.94 | 4.26 | 0.07 |
| Vascular invasion | 2.20 | 1.06 | 4.53 | 0.03 |
AFP: alpha-fetoprotein