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. Author manuscript; available in PMC: 2011 Oct 1.
Published in final edited form as: J Neurochem. 2010 Aug 19;115(1):36–46. doi: 10.1111/j.1471-4159.2010.06894.x

Figure 2. Concentration dependent affects of Mg2+ and Mn2+on the kinase activity of WT, R1441C, G2019S, and I2020T LRRK2 on LRRKtide phosphorylation.

Figure 2

Kinase reactions for (A) WT, (B) R1441C, (C) G2019S and (D) I2020T LRRK2 were conducted using 200µM ATP, 400µM LRRKtide and varying concentrations of Mg2+ or Mn2+ between 0.1 mM and 10 mM. The error bars represent standard error of the mean.