Table 1.

Concentrations of L-arginine, ADMA and SDMA in the medium and cell lysate or cell water of preglomerular vascular smooth muscle cells transfected with p22^phox or wild-type cells transfected with an empty vector

Cell type	Arginine	ADMA	SDMA
	(a) Medium
	μmol·l−1	nmol·l−1
Wt.	529 ± 5	220 ± 7	143 ± 6
S-p22phox	588 ± 2	357 ± 4	135 ± 4
p value:	<0.005	< 0.005	< 0.05
	(b) Calculated concentrations in cell water*
	μmol·l−1	μmol·l−1
Wt.	1,645 ± 63	5.9 ± 1.2	1.6 ± 0.7
S-p22phox	3,222 ± 340	15.7 ± 3.4	4.9 ± 2.7
p value:	<0.005	< 0.005	< 0.05
	(c) Cell: Medium concentration ratio*
Wt.	3.1 ± 0.06	26.9 ± 3.5	11.5 ± 2.8
S-p22phox	5.5 ± 0.33	51.9 ± 13.9	36.1 ± 12.0
p value:	<0.005	< 0.05	< 0.05

Mean ± SEM (n=6 per group);

^*based on a cell water content of cultured vascular smooth muscle cells of 2.53 μl·mg protein⁻¹.¹⁸