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. 2010 Sep 29;21(10):1902–1911. doi: 10.1021/bc100275r

Figure 2.

Figure 2

(A) Fold increase in luciferase expression induced by splicing redirection by incubation of RXR4-PNA705, RXR6-PNA705, and RXR8-PNA705 with HeLa pLuc705 cells. Concentrations of conjugates in each case (left to right) are 0.4, 0.6. 0.8. 1.2, and 1.8 μM. (B) RT-PCR analysis showing aberrant and redirected levels of RNA as a function of concentrations of RXR6-PNA705 or RXR8-PNA705. Concentrations of conjugates (left to right) are the same as in (A), namely, 0.4, 0.6, 0.8, 1.2, and 1.8 μM. NT = cells not treated.