Table 2.
Physiological response to last minute of lower body leg cycling exercise at four different workloads
| Rest |
50 W |
100 W |
150 W |
325 ± 19 W |
|||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Placebo | Fentanyl | Placebo | Fentanyl | Placebo | Fentanyl | Placebo | Fentanyl | Placebo | Fentanyl | ANOVA P Value | |
| Exercise time, min | 3.0 | 3.0 | 3.0 | 3.0 | 3.0 | 3.0 | 4.0 | 4.0 | |||
| % of Wpeak | 13 ± 1 | 13 ± 1 | 25 ± 1 | 25 ± 1 | 38 ± 1 | 38 ± 1 | 80 | 80 | |||
| % of V̇o2max | 27 ± 2 | 27 ± 2 | 37 ± 3 | 37 ± 3 | 48 ± 3 | 48 ± 3 | 87 ± 2 | 87 ± 2 | |||
| V̇e/V̇o2 | 14 ± 0.3 | 14 ± 0.3 | 27.1 ± 1.3 | 25.1 ± 1.6 | 27.7 ± 0.8 | 23.2 ± 0.9* | 28.1 ± 1.7 | 23.7 ± 1.0* | 37.4 ± 1.3 | 36.1 ± 1.5 | 0.006 |
| PetO2, Torr | 98.0 ± 2.4 | 97.9 ± 2.1 | 96.0 ± 1.5 | 90.1 ± 2.6* | 96.9 ± 1.8 | 89.7 ± 1.5* | 97.9 ± 1.5 | 89.5 ± 2.8* | 107.9 ± 1.2 | 104.9 ± 1.2 | 0.014 |
| RPE (dyspnea) | 0.5 ± 0.2 | 0.4 ± 0.1 | 0.9 ± 0.2 | 0.6 ± 0.1 | 1.2 ± 0.2 | 0.7 ± 0.1 | 6.6 ± 0.7 | 5.4 ± 0.8* | 0.005 | ||
| RPE (limb) | 0.2 ± 0.1 | 0.3 ± 0.2 | 0.4 ± 0.2 | 0.5 ± 0.2 | 0.7 ± 0.1 | 0.6 ± 0.1 | 7.3 ± 0.6 | 6.4 ± 0.5* | 0.003 | ||
Values are expressed as means ± SE. Wpeak, peak power output; V̇o2max, maximal O2 consumption (V̇o2); PetO2, end-tidal Po2; RPE, rating of perceived exertion. P value indicates the overall main effect of fentanyl.
*
P < 0.05 vs. placebo.