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. Author manuscript; available in PMC: 2010 Oct 25.
Published in final edited form as: Am J Surg Pathol. 1990 Jun;14(6):538–547. doi: 10.1097/00000478-199006000-00004

TABLE 1.

Clinical features of Epstein-Barr virus (EBV) Syndrome in orthotopic liver transplant recipients

Case no. Age (yr)/sex Primary disease Period of onset of EBV syndrome following transplant (days) Presenting clinical features Outcome of initial EBV syndrome Recurrent EBV syndromes Final outcome of EBV infection
1 53/M CC 63 Fever, pharyngitis, cervical and axillary LN Resolution over 5 wk PTLD lung and ileum resolved over 8 wk Resolution
2 22/M PSC 43 Fever, pharyngitis generalized LN, Sp, icterus Resolution over 8 wk NIL Resolution
3 44/F CC 14 Fever, generalized LN, icterus Resolution over 8 wk NIL Resolution
4 28/F CC 27 Arthralgia right knee, petechial rash Resolution over 2 wk Systemic PTLD, fatal over 1 mo Death
5 20/M CC 603 Fever, pharyngitis, paratracheal LN, diarrhea, jaw pains, arthralgias, right pleural effusion, Sp Developed systemic PTLD, death at 8 wk Death
6 58/M Alcoholic cirrhosis 31 Fever, cervical and axillary LN Resolution over 2 wk Meningoencephalitis resolving over 5 days Resolution
7 26/F α-1ATD 74 Icterus, axillary LN Resolution over 3 wk Systemic PTLD responsive to immunomodulation Resolution
8 18/F Wilson’s 10 Fever, sinus headaches generalized LN Resolution over 3 wk NIL Resolution
9 54/M CAH-B hepatoma 36 Fever, generalized LN Developed systemic PTLD, fatal over 2 wk Not applicable Death
10 42/F CAH cirrhosis 623 Fever, pharyngitis, generalized LN, Sp, ascites, dysarthria, dysmetria, pneumonitis Resolved over 11 wk NIL Resolution

CC, cryptogenic cirrhosis; PSC, primary sclerosing cholangitis; CAH, chronic active hepatitis; α-1ATD, α-1antitrypsin deficiency; LN, lymphadenitis; Sp, splenomegaly; PTLD, posttransplant lymphoproliferative disorders.