Table 2.
1993–1995 | 1996–1998 | 1999–2001 | 2002–2004 | P trend | ||
---|---|---|---|---|---|---|
n | 623 | 464 | 575 | 775 | ||
Sulfonylureas | Any use | 254 (40.8%) | 166 (35.8%) | 213 (37.0%) | 299 (38.6%) | 0.93 |
Alone | 254 (40.8%) | 136 (29.3%) | 102 (17.7%) | 90 (11.6%) | <0.0001 | |
Metformin | Any use | 0 (0%) | 30 (6.5%) | 144 (25.0%) | 287 (37.0%) | <0.0001 |
Alone | 0 (0%) | 1 (0.2%) | 23 (4.0%) | 73 (9.4%) | <0.0001 | |
Thiazolidinediones | Any use | 0 (0%) | 5 (1.1%) | 46 (8.0%) | 154 (19.9%) | <0.0001 |
Alone | 0 (0%) | 0 (0%) | 1 (0.2%) | 2 (0.3%) | 0.06 |
Data are number with percentages of all subjects in each time period in parentheses. “Any use” indicates all subjects reporting use of the drug and “Alone”indicates subjects who are taking the drug as their only therapy for diabetes. Odds ratios are the odds ratios per time period adjusted for age, sex, and diabetes duration. P value for trend adjusted for age, sex, and diabetes duration.