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. 2010 Aug 12;59(11):2697–2707. doi: 10.2337/db10-1032

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© 2010 by the American Diabetes Association.

Readers may use this article as long as the work is properly cited, the use is educational and not for profit, and the work is not altered. See http://creativecommons.org/licenses/by-nc-nd/3.0/ for details.

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FIG. 23. — Plasma glucose concentrations observed during nondiabetic (upper panel) or diabetic (lower panel) insulin profiles when glucagon concentrations were either maintained constant by glucagon infusion started at time zero (nonsuppressed study day) or permitted to decrease by delaying the glucagon infusion until 120 min. A prandial glucose infusion and infusions of somatostatin and growth hormone also were started at time zero (36).