TABLE 1.
Metabolic parameters in B6 vs. 129 mice at different ages and dietary conditions
| Chow diet (21% fat) |
Low-fat diet (14% fat) |
High-fat diet (55% fat) |
||||||
|---|---|---|---|---|---|---|---|---|
| 6 weeks old |
6 months old |
|||||||
| B6 | 129 | B6 | 129 | B6 | 129 | B6 | 129 | |
| Body weight (g) | 21.9 ± 0.6 | 23.5 ± 0.5 | 45.5 ± 1.0 | 30.4 ± 1.2 | 41.5 ± 1.4 | 30.9 ± 1.2 | 46.4 ± 1.1 | 39.2 ± 1.5 |
| Epididymal fat mass (g) | 0.09 ± 0.01 | 0.21 ± 0.02 | 1.67 ± 0.14 | 2.14 ± 0.30 | 1.62 ± 0.17 | 0.58 ± 0.11 | 3.39 ± 0.33 | 3.92 ± 0.14 |
| Blood glucose– random fed (mg/dl) | 155.5 ± 3.1 | 129.3 ± 2.9 | 168.2 ± 12.3 | 106.6 ± 3.5 | 148.5 ± 7.4 | 102.5 ± 3.4 | 153.3 ± 6.7 | 105.5 ± 3.7 |
| Insulin (ng/ml) | 2.26 ± 0.48 | 3.12 ± 0.58 | 92.14 ± 25.71 | 3.96 ± 2.04 | 24.78 ± 12.51 | 1.29 ± 0.32 | 32.73 ± 12.46 | 3.58 ± 0.41 |
| Leptin (ng/ml) | 7.14 ± 0.70 | 9.00 ± 0.90 | 76.18 ± 3.82 | 16.67 ± 4.5 | 72.50 ± 8.06 | 4.97 ± 0.77 | 82.38 ± 7.41 | 46.81 ± 6.02 |
Values are expressed as mean ± SE of 8 animals per group.