TABLE 3. Determination of Insulin, Glucagon, IRI/IRG, Estrogen and Testosterone in Sham-Operated Rats and in PH Rats Treated in our Study with H2 Blocking Agents or Omeprazole.
| Glucagon (pg/ml) | Insulin (μU/ml) | IRI/IRG | Estrogen (pg/ml) | Testosterone (ng/ml) | |
|---|---|---|---|---|---|
| Sham rats | |||||
| control | 180 ± 56 | 27 ± 2 | 3.50 | 8.3 ± 3 | 1.7 ± 0.33 |
| cimetidine | 173 ± 68 | 24 ± 3 | 3.23 | 7.3 ± 2 | 1.3 ± 0.35 |
| ranitidine | 183 ± 22 | 18 ± 7 | 2.29 | 3.5 ± 5 | 1.4 ± 0.15 |
| famotidine | 198 ± 64 | 28 ± 2 | 3.29 | 10.3 ± 4 | 1.5 ± 0.40 |
| omeprazole | 193 ± 85 | 25 ± 3 | 4.10 | 6.4 ± 3 | 2.0 ± 0.50 |
| 70% PH rats | |||||
| control | 410 ± 110 | 20 ± 2.0 | 1.14 | 7.9 ± 2.1 | 0.30 ± 0.03 |
| cimetidine | 460 ± 150 | 24 ± 2.4 | 1.20 | 7.8 ± 3.0 | 0.95 ± 0.01 |
| ranitidine | 540 ± 100 | 29 ± 3.0 | 1.25 | 6.9 ± 4.0 | 0.18 ± 0.02 |
| famotidine | 480 ± 90 | 26 ± 1.5 | 1.26 | 9.3 ± 3.0 | 0.32 ± 0.03 |
| omeprazole | 420 ± 70 | 27 ± 7.2 | 1.50 | 8.1 ± 2.0 | 0.48 ± 0.04 |
Control, saline; cimetidine, 2.4 mg/rat; ranitidine, 0.8 mg/rat; famotidine, 0.11 mg/rat; omeprazole, 0.06 mg/rat.