Figure 2. SMC-PPARγ deficiency augmented AngII-induced atherosclerosis but had no effect on AAAs in male LDL receptor −/− mice.
Atherosclerotic lesion area was measured on aortic arch (A) and thoracic (B) intimal surfaces (n = 9–20). (C) Measurements of maximal external width of abdominal aortas (n = 9–16). Open (Cre0/0) and gray circles (Cre+/0) represent individual mice, diamonds represent means, and bars are SEMs. Statistical analyses were performed using Mann-Whitney Rank Sum analyses. Horizontal bars represents significance of P<0.05.
