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. Author manuscript; available in PMC: 2010 Oct 25.
Published in final edited form as: Arch Gen Psychiatry. 2010 Apr;67(4):423–431. doi: 10.1001/archgenpsychiatry.2010.23

Figure 4. Interaction between rhNPY genotype (T/T, T/G, G/G) and early rearing history (MR, mother- reared, vs. PR, peer-reared) on levels of voluntary alcohol consumption (mean ± SEM).

Figure 4

There was an interaction between rearing condition and genotype on alcohol consumption (F(2, 85) = 3.3, P = 0.04). When given simultaneous access to alcohol (8.4% v/v) and sweetened vehicle in a limited access paradigm, PR monkeys who were carriers of the G allele consumed higher levels of alcohol than did non-stress-exposed (MR) subjects genotype (Tukey-Kramer, P < 0.05). Genotype accounted for 12.5% of the variance in PR monkeys. (MR T/T = 29, MR T/G = 25, MR G/G = 8; PR T/T = 10, PR T/G = 11, PR G/G = 8). Values shown are G/KG alcohol consumed in a 1-hour session (G/KG/H) ± SEM. * P < 0.05.