Table 2. MLPA test for CLL: interpretative criteria and calling guidelines.

Normalized probe ratio	Calling guidelines	Interpretation, p-value
Within Mean ± 2SD	Duplicates show > = 50% probes in the cluster are within this range	Normal
Out of Mean ± 3SD	Duplicates show > = 1 probe in the cluster are out of this range	Deletion or Amplification, P<0.01
Between Mean ± 2SD and Mean ± 3SD	Duplicates show > = 50% probes in the cluster are within this range	Loss or Gain, P<0.05