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. Author manuscript; available in PMC: 2010 Nov 1.
Published in final edited form as: Brain Res. 2010 Sep 21;1361:93–101. doi: 10.1016/j.brainres.2010.09.025

Figure 1.

Figure 1

Primary cultured neurons were pretreated with different doses of thrombin for 24 hours and then exposed to oxygen glucose deprivation (OGD) for 2 hours. The levels of lactate dehydrogenase (LDH) released into the medium (A) and the percent of dead cells by live/dead cell staining (B and C) were measured after 22 hours of reoxygenation. Values are expressed as means ± SD. *p< 0.05, # p< 0.01 vs. control (0 U/ml thrombin). In (C), neurons stained red indicate dead neurons and those green are live. TPC = thrombin preconditioning with 1U/ml. Scale bar = 20 μM.