Fig. 2. Effect of P on behavioral seizures (A), afterdischarge duration (B), and motor activity in fully-kindled WT mice.
Animals were stimulated daily and were used when they exhibited fully kindled (stage 5) seizures on three consecutive days. P (25 and 100 mg/kg) was injected subcutaneously 30 min before stimulation. The motor effects of P are measured by the inverted screen test. Each bar represents the mean ± SEM of data from six to eight animals. *p<0.05 vs. control.
