Table II.

Demographic profiles of and tests of differences between depressed American adolescents aged 12–18 years old and RCTs of MDD in adolescents aged 12–18 years old.

	Depressed American adolescents, as estimated from 1999 YRBS, aged 12–18 Estimate (standard error)	All MDD RCTs of adolescents n = 6, N = 1, 151 Estimate (standard error)	MDD RCTs that excluded high risk n = 5, N = 907 Estimate (standard error)	MDD RCT that did not exclude high risk n = 1, N = 244 Estimate (standard error)
Average age	16.14 (0.04)	14.76 (2.99)	14.46 (2.95)	15.90 (2.86)
Per cent female	62.6 (1.8)	63.8 (1.4)	61.0 (1.6)	74.0 (2.8)
Per cent white	54.1 (3.5)	80.1 (1.2)	75.5 (1.4)	97.0 (1.1)

n denotes the number of RCTs and N denotes the total number of subjects. Bold values represent significant differences between the RCT and YRBS estimates. Variances calculated using the continuity correction (adding $\frac{1}{2}$ to each race count in that study).